Electrical Stimulation: Why we use isolators.

Even though we are now in the era of optogenetics, electrical stimulation of excitable tissues is still common place in the lab. However, despite how common they are, I see that a lot of people don’t fully understand why they using some fancy expensive box to deliver the stimulus, rather than just, say, using the DAC output of your digitizer. The actual physics of why passing current through your tissue excites neurons/muscles is a bit more complex than you might think, but that’s not what I’m going to talk about. I’m going to talk about what a stimulus isolator is, and why we use them. Continue reading